AP-2-containing clathrin coats assemble on mature lysosomes.
نویسندگان
چکیده
منابع مشابه
AP-2-containing clathrin coats assemble on mature lysosomes
Coat proteins appear to play a general role in intracellular protein trafficking by coordinating a membrane budding event with cargo selection. Here we show that the AP-2 adaptor, a clathrin-associated coat-protein complex that nucleates clathrin-coated vesicle formation at the cell surface, can also initiate the assembly of normal polyhedral clathrin coats on dense lysosomes under physiologica...
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vesicles, and possibly at other transport steps. Recent progress has provided insights into molecular interactions that govern clathrin coat dynamics. Now, ter Haar Babak Pishvaee and Gregory S. Payne Department of Biological Chemistry UCLA School of Medicine Los Angeles, California 90095 et al. (1998) report in this issue of Cell the crystal structure of the clathrin heavy chain amino-terminal...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1996
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.135.6.1801